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ABSTRACT.- This report describes the first documented case of intracerebral hemorrhage (ICH) in a horse following Bothrops snakebite envenomation. A 3-year-old mare developed acute kidney injury, systemic hemorrhage, and neurological signs before euthanasia. Postmortem findings confirmed massive ICH with intralesional venom identified by immunohistochemistry. Delayed treatment and insufficient antivenom likely contributed to the outcome. This case highlights the potential for cerebrovascular complications following Bothrops snakebite envenomation in horses, which may present as subtle neurological signs. © 2025 Elsevier Ltd

SOUSA, A.L.V.D., DE SOUSA, D.E.R., DE MACÊDO, I.L., DE ALBUQUERQUE CERQUEIRA, L., DA FONSECA, Y.N.G., OLIVEIRA, A.B., DAS CHAGAS, L.V.S., GONÇALVES, G.B., VEADO, H.C., KELLER, K.M., LOPES CÂMARA, A.C., MACHADO, M., DE CASTRO, MÁRCIO BOTELHO
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Artículos en revistas científicas
65275
null; Acute kidney injury; Brain; Coagulopathy; Equine; Lancehead pit viper; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA; INIA TACUAREMBÓ.
Series
Toxicon, 2025, volume 263, 108408. https://doi.org/10.1016/j.toxicon.2025.108408